EUR_ld.blocks

A GRanges object containing the LD block for European ancestry, in hg19 build.
This dataset was obtained from <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731402/">Belisa and Pickrell (2016)</a>, in bed format,
then converted to GRanges. See manuscript for more details.

datasets

Quickly computes polygenic scores from GWAS summary statistics of either case-control or quantitative traits, without LD matrix computation or parameter tuning. Reales,G., Kelemen,M., Wallace,C. (2020) <doi:10.1101/2020.07.24.220392> "R<c3><a1>pidoPGS: A rapid polygenic score calculator for summary GWAS data without validation dataset".

Guillermo Reales

RapidoPGS

A Fast and Light Package to Compute Polygenic Risk Scores

Chris Wallace

Olly Burren

EUR_ld.blocks function

A GRanges object containing 1703 ranges<dl class="dl-horizontal">
<dt>seqnames</dt><dd>chromosome</dd>
<dt>ranges</dt><dd>start and stop positions for the block</dd>
<dt>strand</dt><dd>genomic strand, irrelevant here</dd>
</dl>

Format

A GRanges object containing the LD block for European ancestry, in hg19 build.
This dataset was obtained from <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731402/'>Belisa and Pickrell (2016)</a>, in bed format,
then converted to GRanges. See manuscript for more details.

LD block architecture for European populations (hg19). — EUR_ld.blocks

A GRanges object containing 1703 ranges<dl class='dl-horizontal'>
<dt>seqnames</dt><dd>chromosome</dd>
<dt>ranges</dt><dd>start and stop positions for the block</dd>
<dt>strand</dt><dd>genomic strand, irrelevant here</dd>
</dl>

EUR_ld.blocks: LD block architecture for European populations (hg19).

Description

Usage

Arguments

Format