EUR_ld.blocks38

A GRanges object containing the LD block for European ancestry, in hg38 build.
This dataset was obtained from <a href="https://www.biorxiv.org/content/10.1101/2022.03.04.483057v1">MacDonald et al. (2022)</a>, in bed format,
then transformed to GRanges.
See manuscript for more details.

datasets

Quickly computes polygenic scores from GWAS summary statistics of either case-control or quantitative traits, without LD matrix computation or parameter tuning. Reales,G., Vigorito, E., Kelemen,M., Wallace,C. (2021) <doi:10.1101/2020.07.24.220392> "RápidoPGS: A rapid polygenic score calculator for summary GWAS data without a test dataset".

Guillermo Reales

RapidoPGS

A Fast and Light Package to Compute Polygenic Risk Scores

Chris Wallace

Olly Burren

EUR_ld.blocks38 function

A GRanges object containing 1361 ranges<dl>
<dt>seqnames</dt>
<dd>chromosome</dd><dt>ranges</dt>
<dd>start and stop positions for the block</dd><dt>strand</dt>
<dd>genomic strand, irrelevant here</dd>
</dl>

Format

A GRanges object containing the LD block for European ancestry, in hg38 build.
This dataset was obtained from <a href='https://www.biorxiv.org/content/10.1101/2022.03.04.483057v1'>MacDonald et al. (2022)</a>, in bed format,
then transformed to GRanges.
See manuscript for more details.

LD block architecture for European populations (hg38). — EUR_ld.blocks38

A GRanges object containing 1361 ranges<dl>
<dt>seqnames</dt>
<dd>chromosome</dd>

<dt>ranges</dt>
<dd>start and stop positions for the block</dd>

<dt>strand</dt>
<dd>genomic strand, irrelevant here</dd>


</dl>

EUR_ld.blocks38: LD block architecture for European populations (hg38).

Description

Usage

Arguments

Format