The data from Kryukov et al, 2009, contain simulated site frequency spectrum data using European demographic models with purifying selection.
data(Kryukov)Kryukov is a dataframe with four columns:
The unit of each variant
The maf of each variant in the European population
The selction coefficient of each variant in the European population
The position of each variant
200 units are present corresponding to 200 genes. For each unit, the data set contains the maf in the European population, the selection coefficient and the position of each variant.
Kryukov et al, 2009, Power of deep, all-exon resequencing for discovery of human trait genes, Proceedings of the National Academy of Sciences, DOI:10.1073/pnas.0812824106