PM_AMP_COAD

Probability matrix, with information of genes being amplified in samples in Colon Adenocarcinoma, created by AMP_COAD.rda applying <code>getPM</code> and used as real example and <code>getMutexAB</code>.

datasets

An optimized method for identifying mutually
exclusive genomic events. Its main contribution is a
statistical analysis based on the Poisson-Binomial
distribution that takes into account that some samples
are more mutated than others. See [Canisius, Sander, John WM Martens,
and Lodewyk FA Wessels. (2016) "A novel independence test for
somatic alterations in cancer shows that
biology drives mutual exclusivity but chance explains
most co-occurrence." Genome biology 17.1 : 1-17. <doi:10.1186/s13059-016-1114-x>].
The mutations matrices are sparse matrices. The method developed takes
advantage of the advantages of this type of matrix to save
time and computing resources.

Juan A. Ferrer-Bonsoms Developer

Rediscover

Identify Mutually Exclusive Mutations

Juan A. Ferrer-Bonsoms

Laura Jareno

Angel Rubio

PM_AMP_COAD function

The format is: 
num [1:1000, 1:391] 0.118 0.118 0.118 0.118 0.114 ...

Format

PM_AMP_COAD data — PM_AMP_COAD

PM_AMP_COAD data

PM_AMP_COAD: PM_AMP_COAD data

Description

Usage

Arguments

Format

Examples