Wrapper to run edgeR: create the dge
object, normalize data, estimate dispersions, statistical testing...
run.edgeR(counts, target, varInt, condRef, batch = NULL, cpmCutoff = 1,
normalizationMethod = "TMM", pAdjustMethod = "BH", ...)
matrix
of counts
target data.frame
of the project
name of the factor of interest (biological condition)
reference biological condition
batch effect to take into account (NULL
by default)
counts-per-million cut-off to filter low counts
normalization method: "TMM"
(default), "RLE"
(DESeq) or "upperquartile"
p-value adjustment method: "BH"
(default) or "BY"
optional arguments to be passed to glmFit()
A list containing the dge
object and the results
object