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SCCS (version 1.1)

The Self-Controlled Case Series Method

Description

Various self-controlled case series models used to investigate associations between time-varying exposures such as vaccines or other drugs or non drug exposures and an adverse event can be fitted. Detailed information on the self-controlled case series method and its extensions with more examples can be found in Farrington, P., Whitaker, H., and Ghebremichael Weldeselassie, Y. (2018, ISBN: 978-1-4987-8159-6. Self-controlled Case Series studies: A modelling Guide with R. Boca Raton: Chapman & Hall/CRC Press) and .

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Version

Install

install.packages('SCCS')

Monthly Downloads

367

Version

1.1

License

GPL (>= 2)

Maintainer

Yonas Ghebremichael-Weldeselassie

Last Published

June 4th, 2019

Functions in SCCS (1.1)

Data on antidiabetics and fractures

Data on DTP and convulsions

Data on antipsychotics and stroke

The Self-Controlled Case Series (SCCS) Method

Data on blood pressure and headaches

Data on bupropion and sudden death

Data on NSAID and antidepressant exposure and first GI bleed

Data on MMR and aseptic meningitis

Data on DTP and convulsions

Data on MMR vaccine and autism

Data on DTP, Hib and convulsions

Data on antidepressants and hip fracture

Data on Rotavirus vaccine and intussusception

Data on RSV and ambient temperature

Data on MMR and ITP

Data on intussusception and OPV

integrateIspline

Integral of I-splines

Likelihood ratio test for SCCS models

The standard SCCS method

Sample size calculation in SCCS

SCCS with event-dependent exposure

Semiparametric self-controlled case series method

Data on NRT and MI

SCCS with event-dependent observation periods

Data on OPV and intussusception

Spline-based semiparametric SCCS, smooth age

Spline-based semiparametric SCCS, smooth exposure

Data on multitype convulsions and MMR

Formatting data

Data on respiratory tract infections and myocardial infarction

Data on influenza vaccine and GBS

Spline-based non parametric SCCS method

simulatesccsdata

Simulation of SCCS data

Data on asthma admissions and air pollution

Data on NSAID and first GI bleed

Data on hexavalent vaccine and sudden infant death syndrome (SIDS)

Quantitative exposures in self controlled case series method