For each stage in selected_stages, starting from the markers given by markers_cluster_seurat function of the package CIARA, only the markers with a median above threshold in the stage and below threshold in all the other stages are kept.
select_top_markers(
selected_stages,
cluster_vivo,
norm_vivo,
markers_small,
max_number = 100,
threshold = 0.1
)A list with two elements:
Vector with the union of all the top_number markers for each stage in selected_stages
List with length equal to number of stages in selected_stages . Each element contains the top_number markers for a given stage in selected_stages
Character vector with the name of the selected in vivo stages
cluster for in vivo dataset
Norm count matrix (n_genes X n_cells) for in vivo dataset
Output given by the function markers_cluster_seurat of the package CIARA
Numeric value. Maximum number of top markers to consider for each stage in selected_stages
Numeric value.
Gabriele Lubatti gabriele.lubatti@helmholtz-muenchen.de