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SEARS (version 0.1.0)

Seamless Dose Escalation/Expansion with Adaptive Randomization Scheme

Description

A seamless design that combines phase I dose escalation based on toxicity with phase II dose expansion and dose comparison based on efficacy.

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Version

Install

install.packages('SEARS')

Monthly Downloads

138

Version

0.1.0

License

GPL-2

Maintainer

Chia-Wei Hsu

Last Published

June 29th, 2023

Functions in SEARS (0.1.0)

SEARS

A randomized distributed phase I-II seamless dose escalation/expansion schema for dose optimization and selection in early oncology clinical development