Systematic Identification of Bimodally Expressed Genes Using
RNAseq Data
Description
Provides models to identify bimodally expressed genes from
RNAseq data based on the Bimodality Index. SIBERG models the RNAseq data in
the finite mixture modeling framework and incorporates mechanisms for
dealing with RNAseq normalization. Three types of mixture models are
implemented, namely, the mixture of log normal, negative binomial, or
generalized Poisson distribution. See Tong et al. (2013)
.