progressionDAG_from_igraph

An igraph object for a directed acyclic graph.

A helper function for <code><a rd-options="" href="/link/simulateTumor?package=SITH&version=1.1.0" data-mini-rdoc="SITH::simulateTumor">simulateTumor</a>()</code> which returns to the user
the edge list for a DAG which is defined as an <code>igraph</code> object.

Implements a three-dimensional stochastic model of cancer growth and mutation similar to the one described in Waclaw et al. (2015) <doi:10.1038/nature14971>. Allows for interactive 3D visualizations of the simulated tumor. Provides a comprehensive summary of the spatial distribution of mutants within the tumor. Contains functions which create synthetic sequencing datasets from the generated tumor.

Phillip Nicol

SITH

A Spatial Model of Intra-Tumor Heterogeneity

progressionDAG_from_igraph function

A helper function for <code><a rd-options='' href='simulateTumor'>simulateTumor</a>()</code> which returns to the user
the edge list for a DAG which is defined as an <code>igraph</code> object.

progressionDAG_from_igraph: Define the progression of mutations from an `igraph` object

Description

Usage

Arguments

Value