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SKAT (version 2.2.4)
SNP-Set (Sequence) Kernel Association Test
Description
Functions for kernel-regression-based association tests including Burden test, SKAT and SKAT-O. These methods aggregate individual SNP score statistics in a SNP set and efficiently compute SNP-set level p-values. Methods available in this package include SKAT described in Micheal Wu, Seunggeun Lee et al. (2011) , SKAT-O in Seunggeun Lee et al. (2012) , combined test of rare and common variants in Iuliana Ionita-Laza and Seunggeun Lee et al. (2013) , efficient resampling for binary traits in Seunggeun Lee et al. (2016) , and robust test for binary traits in Zhangchen Zhao et al. (2020) .