Get_EffectiveNumberTest

Estimate the effective number of tests for Bonferroni correction using the minimum achievable p-values (MAP).

Functions for kernel-regression-based association tests including Burden test, SKAT and SKAT-O. These methods aggregate individual SNP score statistics in a SNP set and efficiently compute SNP-set level p-values.

Seunggeun Lee

SKAT

SNP-Set (Sequence) Kernel Association Test

Get_EffectiveNumberTest function

<dl> <dt>MAP</dt>
<dd>a vector of the minimum achievable p-values (MAP).</dd> <dt>alpha</dt>
<dd>a significant level.</dd> <dt>Is.MidP</dt>
<dd>a logical value indicating whether p-values are mid-p-values.</dd></dl>

Arguments

Author

Estimate the effective number of tests for Bonferroni correction — Get_EffectiveNumberTest

<dl>

 <dt>MAP</dt>
<dd>a vector of the minimum achievable p-values (MAP).</dd>

 <dt>alpha</dt>
<dd>a significant level.</dd>

 <dt>Is.MidP</dt>
<dd>a logical value indicating whether p-values are mid-p-values.</dd>

</dl>

Get_EffectiveNumberTest: Estimate the effective number of tests for Bonferroni correction

Description

Usage

Value

Arguments

Author

References