SKAT.example

Functions for kernel-regression-based association tests including Burden test, SKAT and SKAT-O. These methods aggregate individual SNP score statistics in a SNP set and efficiently compute SNP-set level p-values.

Seunggeun Lee

SKAT

SNP-Set (Sequence) Kernel Association Test

SKAT.example function

SKAT.example contains the following objects:<dl>
 <dt>Z</dt>
<dd>a numeric genotype matrix of 2000 individuals and 67 SNPs. 
	Each row represents a different individual, and each column represents a different SNP marker.</dd> <dt>X</dt>
<dd>a numeric matrix of 2 covariates.</dd> <dt>y.c</dt>
<dd>a numeric vector of continuous phenotypes.</dd> <dt>y.b</dt>
<dd>a numeric vector of binary phenotypes.</dd> 
</dl>

Format

Example data for SKAT — SKAT.example

SKAT.example contains the following objects:<dl>
 <dt>Z</dt>
<dd>a numeric genotype matrix of 2000 individuals and 67 SNPs. 
	Each row represents a different individual, and each column represents a different SNP marker.</dd>

 <dt>X</dt>
<dd>a numeric matrix of 2 covariates.</dd>

 <dt>y.c</dt>
<dd>a numeric vector of continuous phenotypes.</dd>

 <dt>y.b</dt>
<dd>a numeric vector of binary phenotypes.</dd>

 
</dl>

SKAT.example: Example data for SKAT

Description

Arguments

Format