SLGI (version 1.32.0)

gi2005: Genetic Interaction Data (EMAP) from the yeast early secretory pathway

Description

The data are in the form of a 424 by 424 array which contains the scores from using the EMAP procedure on yeast strains which are ideally double mutants, each strain with a different pair of genes knocked out. For each row, the gene named in the row label is knocked out in all pairs, and the same holds true for each column.

Usage

data(gi2005) data(gi2005.metadata)

Format

gi2005 is a 424 by 424 array of real values. gi2005.metadata is a vector of length 424 which contains the common names for the genes that were knocked out. The row and column names of gi2005 are standard names.

Source

Data were obtained as supplementary material from the publication listed below.

Details

NA values in gi2005 are interactions that were not scored.

References

Schuldiner et al, Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell, 2005, 123:507-519.

Collins et al, A strategy for extracting and analyzing large-scale quantitative epistatic interaction data. Genome Biology, 2006, 7:R63.

Examples

data(gi2005)
data(gi2005.metadata)