SLGI (version 1.32.0)

iSummary: Summarize cellular organizational units sharing genetic interaction

Description

Summarize the cellular organizational units sharing genetic interactions and display their GO annotation if available

Usage

iSummary(iMat, n=10, reverse=FALSE)

Arguments

iMat

Comembership matrix of genes(proteins) that linked to other genes(proteins) by any biological experiment, e.g., output of the getInteraction function.

n

Numeric threshold indicating the minimum number of genetic interactions that a pair of cellular organizational unit must share.

reverse

Logical, by default the function return a list of pair of cellular organizational units where the name of each element is the number of genetic interactions they share. If reverse is TRUE, the output is a vector where the values are the number of interactions and the names are the combination of the 2 cellular organizational units.

Value

The function print the result in the standard output but can also save it in variable.If reverse is FALSE the output is a list of pairs of cellular organizational units where the name of each element is the number of genetic interactions they share.If reverse is TRUE the output is a vector where the values are the number of interactions and the names are the combination of the 2 cellular organizational units.

Examples

data(Atong)
data(ScISIC)
data(SGA)
SLa2 <- gi2Interactome(Atong, ScISIC)
## Search for synthetic lethal interaction
compM <- getInteraction(SLa2, SGA, ScISIC)
## Display the tightly interacting pairs
largeInt <- iSummary(compM$bwMat,n=15)