run_stringdb_annotation

This function takes a vector of gene symbols, retrieves their interaction partners
from STRING DB, and performs functional enrichment analysis.

To automated functional annotation of genetic variants and linked proxies. Linked SNPs in moderate to high linkage disequilibrium (e.g. r2>0.50) with the corresponding index SNPs will be selected for further analysis.

Alireza Ani

SNPannotator

Automated Functional Annotation of Genetic Variants and Linked
Proxies

Zoha Kamali

Ahmad Vaez

run_stringdb_annotation function

<dl><dt>name</dt>
<dd>A character string specifying a unique identifier for this analysis run.</dd>
<dt>gene_list</dt>
<dd>A character vector of gene symbols (e.g., HGNC symbols or Ensembl gene IDs).</dd>
<dt>required_score</dt>
<dd>Threshold of significance to include an interaction, a number between 0 and 1000.</dd>
<dt>limit</dt>
<dd>Limits the number of interaction partners retrieved per protein, a number between 0 and 100.</dd>
<dt>...</dt>
<dd>Additional arguments passed to downstream functions for extended customization.</dd></dl>

Arguments

Analyze STRING DB Interactions and perform functional enrichment — run_stringdb_annotation

<dl>

<dt>name</dt>
<dd>A character string specifying a unique identifier for this analysis run.</dd>


<dt>gene_list</dt>
<dd>A character vector of gene symbols (e.g., HGNC symbols or Ensembl gene IDs).</dd>


<dt>required_score</dt>
<dd>Threshold of significance to include an interaction, a number between 0 and 1000.</dd>


<dt>limit</dt>
<dd>Limits the number of interaction partners retrieved per protein, a number between 0 and 100.</dd>


<dt>...</dt>
<dd>Additional arguments passed to downstream functions for extended customization.</dd>

</dl>

run_stringdb_annotation: Analyze STRING DB Interactions and perform functional enrichment

Description

Usage

Value

Arguments