SPEM (version 1.12.0)

sos: SOS pathway time series data

Description

In this package we offer the SOS data obtained from Uri Alon's lab (http://www.weizmann.ac.il/mcb/UriAlon/). SOS response is a general DNA repair system in bacteria which allows survival after DNA damage. This SOS dataset is taken from real experiment expression data in Escherichia coli. It contains 8 genes under Experiment 3 (UV light intensities, 4:20 Jm^(-2)).

Usage

data(sos)

Format

sos.data is time series gene expression value data in ExpressionSet Class. assayData: Matrix with expression values of 8 genes in SOS pathway of Escherichia coli. These expression levels are observed at 50 time points. phenoData: Sample data.frame includes label "time", which represents the value of time points.

References

M. Ronen, R. Rosenberg, B. I. Shraiman, and U. Alon. Assigning numbers to the arrows: parameterizing a gene regulation network by using accurate expression kinetics. Proceedings of the National Academy of Sciences of the United States of America, Aug. 2002. PMID: 12145321.

Examples

data(sos)