cyclicSplineDesign

Create a design matrix for a cyclic spline

Execute the self-controlled case series (SCCS) design using observational
data in the OMOP Common Data Model. Extracts all necessary data from the database and
transforms it to the format required for SCCS. Age and season can be modeled
using splines assuming constant hazard within calendar months. Event-dependent
censoring of the observation period can be corrected for. Many exposures can be
included at once (MSCCS), with regularization on all coefficients except for the
exposure of interest. Includes diagnostics for all major assumptions of the SCCS.

Martijn Schuemie

SelfControlledCaseSeries

Self-Controlled Case Series

Patrick Ryan

Trevor Shaddox

Marc Suchard

cyclicSplineDesign function

<dl><dt>x</dt>
<dd>Vector of coordinates of the points to be interpolated.</dd>
<dt>knots</dt>
<dd>Location of the knots.</dd>
<dt>ord</dt>
<dd>Order of the spline function. <code>ord = 3</code> implies quadratic.</dd></dl>

Arguments

Create a design matrix for a cyclic spline — cyclicSplineDesign

<dl>

<dt>x</dt>
<dd>Vector of coordinates of the points to be interpolated.</dd>


<dt>knots</dt>
<dd>Location of the knots.</dd>


<dt>ord</dt>
<dd>Order of the spline function. <code>ord = 3</code> implies quadratic.</dd>

</dl>

cyclicSplineDesign: Create a design matrix for a cyclic spline

Description

Usage

Arguments

Details