add_modules_to_network

network

<p>A list of 'network_module' objects to add to the network.</p>

module_list

<p>Internal function for adding a set of modules to the network</p>

Methods to generate random gene-gene association networks and simulate RNA-seq data from them, as described in Grimes and Datta (2021) <doi:10.18637/jss.v098.i12>. Includes functions to generate random networks of any size and perturb them to obtain differential networks. Network objects are built from individual, overlapping modules that represent pathways. The resulting network has various topological properties that are characteristic of gene regulatory networks. RNA-seq data can be generated such that the association among gene expression profiles reflect the underlying network. A reference RNA-seq dataset can be provided to model realistic marginal distributions. Plotting functions are available to visualize a network, compare two networks, and compare the expression of two genes across multiple networks.

Tyler Grimes

add_modules_to_network: Internal function for adding a set of modules to the network

Description

Usage

Arguments

Value