get_network_characteristics

A 'network', 'network_module', or 'matrix' object.

network

If <code>TRUE</code>, only the global characteristics are calculated.

global_only

The average degree, clustering coefficient, and average path length are calculated.

Methods to generate random gene-gene association networks and simulate RNA-seq data from them, as described in Grimes and Datta (2021) <doi:10.18637/jss.v098.i12>. Includes functions to generate random networks of any size and perturb them to obtain differential networks. Network objects are built from individual, overlapping modules that represent pathways. The resulting network has various topological properties that are characteristic of gene regulatory networks. RNA-seq data can be generated such that the association among gene expression profiles reflect the underlying network. A reference RNA-seq dataset can be provided to model realistic marginal distributions. Plotting functions are available to visualize a network, compare two networks, and compare the expression of two genes across multiple networks.

get_network_characteristics: Characteristics of the network topology

Description

Usage

Arguments

Value

Examples