Seurat (version 2.3.4)

RefinedMapping: Quantitative refinement of spatial inferences

Description

Refines the initial mapping with more complex models that allow gene expression to vary quantitatively across bins (instead of 'on' or 'off'), and that also considers the covariance structure between genes.

Usage

RefinedMapping(object, genes.use)

Arguments

object

Seurat object

genes.use

Genes to use to drive the refinement procedure.

Value

Seurat object, where mapping probabilities for each bin are stored in [e-mail]

Details

Full details given in spatial mapping manuscript.

Examples

# NOT RUN {
# Note that the PBMC test example object does not contain spatially restricted
# examples below are only demonstrate code
pmbc_small <- RefinedMapping(pbmc_small, genes.use=[e-mail])
# }
# NOT RUN {
# }