norm_FDR_SQAUC

norm_FDR_SQAUC
The function controls the false discovery rate (FDR) of coexpression patterns
using SQAUC method
Jichun Xie and Ruosha Li. "False discovery rate control for high dimensional
networks of quantile associations conditioning on covariates".
In: J R Stat Soc Series B Stat Methodol (2018). doi: 10.1111/rssb.12288.

Cluster-independent method based on topology structure of gene co-expression network for identifying feature gene sets, extracting cellular subpopulations, and elucidating intrinsic relationships among these subpopulations. Without prior cell clustering, SifiNet circumvents potential inaccuracies in clustering that may influence subsequent analyses. This method is introduced in Qi Gao, Zhicheng Ji, Liuyang Wang, Kouros Owzar, Qi-Jing Li, Cliburn Chan, Jichun Xie "SifiNet: a robust and accurate method to identify feature gene sets and annotate cells" (2024) <doi:10.1093/nar/gkae307>.

Qi Gao

SiFINeT

Single Cell Feature Identification with Network Topology

norm_FDR_SQAUC function

<dl><dt>value</dt>
<dd>the vector of coexpression patterns</dd>
<dt>sam_mean</dt>
<dd>the estimated sample mean</dd>
<dt>sam_sd</dt>
<dd>the estimated sample sd</dd>
<dt>alpha</dt>
<dd>the type I error rate</dd>
<dt>n</dt>
<dd>the number of cells</dd>
<dt>p</dt>
<dd>the number of genes</dd></dl>

Arguments

norm_FDR_SQAUC
The function controls the false discovery rate (FDR) of coexpression patterns
using SQAUC method
Jichun Xie and Ruosha Li. "False discovery rate control for high dimensional
networks of quantile associations conditioning on covariates".
In: J R Stat Soc Series B Stat Methodol (2018). doi: 10.1111/rssb.12288. — norm_FDR_SQAUC

<dl>

<dt>value</dt>
<dd>the vector of coexpression patterns</dd>


<dt>sam_mean</dt>
<dd>the estimated sample mean</dd>


<dt>sam_sd</dt>
<dd>the estimated sample sd</dd>


<dt>alpha</dt>
<dd>the type I error rate</dd>


<dt>n</dt>
<dd>the number of cells</dd>


<dt>p</dt>
<dd>the number of genes</dd>

</dl>

norm_FDR_SQAUC
The function controls the false discovery rate (FDR) of coexpression patterns
using SQAUC method
Jichun Xie and Ruosha Li. "False discovery rate control for high dimensional
networks of quantile associations conditioning on covariates".
In: J R Stat Soc Series B Stat Methodol (2018). doi: 10.1111/rssb.12288.

Description

Usage

Value

Arguments