coagulation

Three sets of extracorporeal circulation in heart-lung machines: treatments H and B, and
standard S. Twelve (S and H each) and eleven (B) male adult patients. The analysis is
based on a set of laboratory parameters restricted to the blood coagulation system,
characterized by three primary endpoints (each as quotient from post- and pre-surgery
values). Higher values indicate a better treatment effect. For more details, see Kropf
et. al, 2000.

datasets

Simultaneous tests and confidence intervals for one-way
        experimental designs with one or many normally distributed,
        primary response variables (endpoints). The procedure of Hasler
        and Hothorn (2011) is applied for differences or ratios of
        means. Various contrasts can be chosen, unbalanced sample sizes
        are allowed as well as heterogeneous variances or covariance
        matrices.

Mario Hasler

SimComp

Simultaneous Comparisons for Multiple Endpoints

coagulation function

Kropf, S. et al. (2000): Multiple comparisons of treatments with stable multivariate tests
in a two-stage adaptive design, including a test for non-inferiority. <em>Biometrical
Journal</em> 42, 951-965.

coagulation: Data from a clinical study of three sets of extracorporeal circulation in heart-lung machines

Description

Usage

Arguments

source

References

Examples