SimEvolEnzCons (version 2.0.0)

mut.kin: Mutation of kinetic parameters

Description

Computes the mutant value of enzyme kinetic parameters

Usage

mut.kin(kin_fun,i_fun,nu_fun,typ_A=1)

Arguments

kin_fun

Numeric vector of enzyme kinetic parameter, which are the resident values

i_fun

Numeric value indicating the number of the enzyme targeted by the mutation

nu_fun

Numeric value of mutation size

typ_A

Numeric for mutation method. Default is 1. See details in mut.kin.

Value

Numeric vector of mutant values of enzyme kinetic parameters

Details

This function used three mutation methods:

• Additive method (typ_A=1): mutant kinetic parameter is the sum of the resident one plus size of mutation \(\nu\)

• Multiplicative method (typ_A=2): mutant kinetic parameter is the product of the resident one and \(1+\nu\)

• Random method (typ_A=3): mutant kinetic parameter is equal to the mutation size

The method 1 is the default one.

See Also

See function mut.E.direct to compute mutation for enzyme concentrations.

See function activities to compute "activities" from enzyme kinetic parameters.

Examples

# NOT RUN {
kin <- c(1,10,1000)
mu <- 1 #size of mutation
i <- 3 #enzyme directly targeted by mutation

mut.kin(kin,i,mu)

# }