SimNPH-package

SimNPH

SimNPH: Simulate Non Proportional Hazards

internal

A toolkit for simulation studies concerning time-to-event endpoints
with non-proportional hazards. 'SimNPH' encompasses functions for simulating
time-to-event data in various scenarios, simulating different trial designs
like fixed-followup, event-driven, and group sequential designs. The package
provides functions to calculate the true values of common summary statistics
for the implemented scenarios and offers common analysis methods for
time-to-event data. Helper functions for running simulations with the
'SimDesign' package and for aggregating and presenting the results are also
included. Results of the conducted simulation study are available in the
paper: "A Comparison of Statistical Methods for Time-To-Event Analyses in
Randomized Controlled Trials Under Non-Proportional Hazards",
Klinglmüller et al. (2025) <doi:10.1002/sim.70019>.

Tobias Fellinger

Simulate Non-Proportional Hazards

Florian Klinglmueller

SimNPH function

Maintainer: Tobias Fellinger <a href="/link/tobias.fellinger%40ages.at?package=SimNPH&version=0.5.7" data-mini-rdoc="SimNPH::tobias.fellinger@ages.at">tobias.fellinger@ages.at</a> (<a href="https://orcid.org/0000-0001-9474-2731">ORCID</a>)
Authors:<ul>
<li>Florian Klinglmueller (<a href="https://orcid.org/0000-0002-7346-3669">ORCID</a>)</li>
</ul>

Author

SimNPH — SimNPH

Maintainer: Tobias Fellinger <a href='mailto:tobias.fellinger@ages.at'>tobias.fellinger@ages.at</a> (<a href='https://orcid.org/0000-0001-9474-2731'>ORCID</a>)
Authors:<ul>
<li>Florian Klinglmueller (<a href='https://orcid.org/0000-0002-7346-3669'>ORCID</a>)</li>
</ul>

SimNPH: SimNPH

Description

Arguments

Author

Details

See Also