create_mate

Data.frame with 1 row. All pedigree information for the individual requiring a new mate, must contain all fields generated by <code><a rd-options="" href="/link/create_pedFile?package=SimRVPedigree&version=0.3.0" data-mini-rdoc="SimRVPedigree::create_pedFile">create_pedFile</a></code>.

partner_info

Numeric. The last id used in the pedigree.

last_id

Numeric. The genetic relative-risk of disease, i.e. the relative-risk of disease for individuals who carry at least one copy of the causal variant.

Numeric. The carrier probability for all causal variants with relative-risk of disease <code>GRR</code>. By default, <code>carrier_prob</code><code> = 0.002</code>

carrier_prob

Logical. Indicates if all pedigrees segregate the rare, causal variant. By default, <code>RVfounder = FALSE</code> See details.

RVfounder

Create new mating partner in pedigree.

internal

Routines to simulate and manipulate pedigrees ascertained to
contain multiple family members affected by a rare disease.
Christina Nieuwoudt, Samantha J Jones, Angela Brooks-Wilson,
and Jinko Graham (2018) <doi:10.1101/234153>.

Christina Nieuwoudt

SimRVPedigree

Simulate Pedigrees Ascertained for a Rare Disease

Jinko Graham

create_mate function

Data.frame with 1 row. All pedigree information for the individual requiring a new mate, must contain all fields generated by <code><a rd-options='' href='create_pedFile'>create_pedFile</a></code>.

create_mate: Create a new mate

Description

Usage

Arguments

Value