disqualify_ped

An object of class <code>ped</code>. A pedigree generated by <code>sim_ped</code> or <code>sim_RVped</code>, or an object created by the function <code><a rd-options="" href="/link/new.ped?package=SimRVPedigree&version=0.3.0" data-mini-rdoc="SimRVPedigree::new.ped">new.ped</a></code>. See details.

ped_file

Numeric. The minimum number of affected individuals in the pedigree.

num_affected

Numeric vector of length 2. The year span of the ascertainment period. This period represents the range of years during which the proband developed disease and the family would have been ascertained for multiple affected relatives.

ascertain_span

Numeric. The first year that reliable diagnoses can be obtained regarding disease-affection status. By default, <code>first_diagnosis</code><code> = NULL</code> so that all diagnoses are considered reliable. See details.

first_diagnosis

Initial checks to disqualify a pedigree from ascertainment.

internal

Routines to simulate and manipulate pedigrees ascertained to
contain multiple family members affected by a rare disease.
Christina Nieuwoudt, Samantha J Jones, Angela Brooks-Wilson,
and Jinko Graham (2018) <doi:10.1101/234153>.

Christina Nieuwoudt

SimRVPedigree

Simulate Pedigrees Ascertained for a Rare Disease

Jinko Graham

disqualify_ped function

An object of class <code>ped</code>. A pedigree generated by <code>sim_ped</code> or <code>sim_RVped</code>, or an object created by the function <code><a rd-options='' href='new.ped'>new.ped</a></code>. See details.

disqualify_ped: Initial checks to disqualify a pedigree from ascertainment.

Description

Usage

Arguments

Value