This data set contains ped data for five ascertiained pedigrees. The ascertained pedigrees were simulated by the sim_RVped function, which is included with the R package SimRVPedigree.
data(study_peds)A data frame with 77 rows and 15 variables:
Family identification number.
Individual identification number.
Sex identification variable: sex = 0 for males, and sex = 1 females.
Identification number of father
Identification number of mother
disease-affection status: affected = TRUE if individual has developed disease, and FALSE otherwise.
Paternally inherited allele at the familial disease locus: DA1 = 1 if the casual variant is inherited, and 0 otherwise.
Maternally inherited allele at the familial disease locus: DA2 = 1 if the casual variant is inherited, and 0 otherwise.
The individual's birth year.
The individual's year of disease onset, when applicable, and NA otherwise.
The individual's year of death, when applicable, and NA otherwise.
The subject's relative-risk of disease
Availability status: available = TRUE if individual is recalled by the proband, and FALSE if not recalled or a marry-in.
The individual's generation number relative to the eldest pedigree founder. That is, the seed founder will have Gen = 1, his or her offspring will have Gen = 2, etc.
Proband identification variable: proband = TRUE if the individual is the proband, and FALSE otherwise.
Christina Nieuwoudt and Jinko Graham (2018).SimRVPedigree:Simulate Pedigrees Ascertained for a Rare Disease.R package version 0.3.0.https://CRAN.R-project.org/package=SimRVPedigree.