SingleCellAssay (version 0.80)

LRT: Likelihood Ratio Tests for SingleCellAssays

Description

Tests for a change in ET binomial proportion or mean of positive ET Likelihood Ratio Test for SingleCellAssay objects

Usage

LRT(sca, comparison, ...)
# S4 method for SingleCellAssay,character
LRT(sca, comparison, referent = NULL,
  groups = NULL, returnall = FALSE)

Arguments

sca

A SingleCellAssay class object

comparison

A character specifying the factor for comparison

referent

A character specifying the reference level of comparison.

groups

A optional character specifying a variable on which to stratify the test. For each level of groups, there will be a separate likelihood ratio test.

returnall

A logical specifying if additional columns should be returned with information about the different components of the test.

Details

Combined Likelihood ratio test (binomial and normal) for SingleCellAssay and derived objects