ex1620: Differential Gene Expression with RNA Sequencing
Description
In an experiment to identify genes of the plant Arabidopsis that react to a
particular pathogen, researchers used RNA sequencing to produce gene profiles
for a number of plants not subjected to the pathogen and several plants
subjected to the pathogen. Tests comparing the distribution of gene expression
in the two groups were performed for each gene individually. The data are the
p-values from all these tests. The goal is to use a identify a set of genes
that differentially express in the two groups, subject to some specified value
for expected false discovery rate, such as 5%.source
Ramsey, F.L. and Schafer, D.W. (2013). The Statistical Sleuth: A
Course in Methods of Data Analysis (3rd ed), Cengage Learning.References
Chang, J, Department of Botany and Plant Pathology, Oregon State University,
personnal communication.