pen_calculator

Calculated penalty parameter for mean size.

lambda1

Calculated penalty parameter for mean difference.

lambda2

Vector containing the number of samples in each dimension.

Small term to ensure existance of solution, default is
0.0000001.

delta

Calcualtes the penalty terms for penalizing mean size and mean difference.
This function runs inside <code>sparse_mdc</code>.

Implements the algorithm described in
Barron, M., and Li, J. (Not yet published). This algorithm clusters
samples from multiple ordered populations, links the clusters across the
conditions and identifies marker genes for these changes. The package was
designed for scRNA-Seq data but is also applicable to many other data
types, just replace cells with samples and genes with variables. The
package also contains functions for estimating the parameters for SparseMDC
as outlined in the paper. We recommend that users further select their
marker genes using the magnitude of the cluster centers.

pen_calculator: Penalty calculator

Description

Usage

Arguments

Value