Surrogate (version 1.7)

Schizo_BinCont: Data of a clinical trial in schizophrenia, with binary and continuous endpoints

Description

These are the data of a clinical trial in schizophrenia. Patients' schizophrenic symptoms were measured using the PANSS, BPRS, and CGI. There were two treatment conditions (risperidone and control).

Usage

data(Schizo)

Arguments

Format

A data.frame with \(446\) observations on \(9\) variables.

Id

The patient ID.

InvestID

The ID of the investigator (psychiatrist) who treated the patient.

Treat

The treatment indicator, coded as \(-1\) = control and \(1\) = Risperidone.

CGI

The change in the CGI score (= score at the start of the treatment - score at the end of the treatment).

PANSS

The change in the PANSS score (= score at the start of the treatment - score at the end of the treatment).

BPRS

The change in the PANSS score (= score at the start of the treatment - score at the end of the treatment).

PANSS_Bin

The dichotomized PANSS change score, coded as \(1\) = a reduction of 20% or more in the PANSS score (score at the end of the treatment relative to score at the beginning of the treatment), \(0\) = otherwise.

BPRS_Bin

The dichotomized BPRS change score, coded as \(1\) = a reduction of 20% or more in the BPRS score (score at the end of the treatment relative to score at the beginning of the treatment), \(0\) = otherwise.

CGI_Bin

The sichtomized change in the CGI score, coded as \(1\) = a change of more than \(3\) points on the original scale (score at the end of the treatment relative to score at the beginning of the treatment), \(0\) = otherwise.