delta.estimate.RMST

Helper function; used by delta.estimate function

internal

Estimates the proportion of treatment effect on a censored primary outcome that is explained by the treatment effect on a censored surrogate outcome/event. All methods are described in detail in Parast, et al (2020) "Assessing the Value of a Censored Surrogate Outcome" <doi:10.1007/s10985-019-09473-1> and Wang et al (2025) "Model-free Approach to Evaluate a Censored Intermediate Outcome as a Surrogate for Overall Survival" <doi:10.1002/sim.70268>. A tutorial for this package can be found at <https://www.laylaparast.com/surrogateoutcome>.

Layla Parast

SurrogateOutcome

Estimation of the Proportion of Treatment Effect Explained by
Surrogate Outcome Information

Xuan Wang

delta.estimate.RMST function

<dl> <dt>xone</dt>
<dd>numeric vector, observed event times for the primary outcome in the treatment group.</dd> <dt>xzero</dt>
<dd>numeric vector, observed event times for the primary outcome in the control group.</dd> <dt>deltaone</dt>
<dd>numeric vector, event/censoring indicators for the primary outcome in the treatment group.</dd> <dt>deltazero</dt>
<dd>numeric vector, event/censoring indicators for the primary outcome in the control group.</dd> <dt>t</dt>
<dd>time of interest for treatment effect.</dd> <dt>weight</dt>
<dd>weight; optional</dd> <dt>delta.only</dt>
<dd>TRUE or FALSE; if TRUE then only delta is returned, if FALSE then delta and restricted mean survival time for each treatment group is also returned</dd></dl>

Arguments

Layla Parast

Author

Helper function — delta.estimate.RMST

<dl>

 <dt>xone</dt>
<dd>numeric vector, observed event times for the primary outcome in the treatment group.</dd>

 <dt>xzero</dt>
<dd>numeric vector, observed event times for the primary outcome in the control group.</dd>

 <dt>deltaone</dt>
<dd>numeric vector, event/censoring indicators for the primary outcome in the treatment group.</dd>

 <dt>deltazero</dt>
<dd>numeric vector, event/censoring indicators for the primary outcome in the control group.</dd>

 <dt>t</dt>
<dd>time of interest for treatment effect.</dd>

 <dt>weight</dt>
<dd>weight; optional</dd>

 <dt>delta.only</dt>
<dd>TRUE or FALSE; if TRUE then only delta is returned, if FALSE then delta and restricted mean survival time for each treatment group is also returned</dd>

</dl>

delta.estimate.RMST: Helper function

Description

Usage

Value

Arguments

Author