# SurvGSD v1.0.0

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## Group Sequential Design for a Clinical Trial with Censored Survival Data

Sample size calculation utilizing the information fraction and the alpha spending function in a group sequential clinical trial with censored survival data from underlying generalized gamma survival distributions or log-logistic survival distributions. Hsu, C.-H., Chen, C.-H, Hsu, K.-N. and Lu, Y.-H. (2018) A useful design utilizing the information fraction in a group sequential clinical trial with censored survival data. To appear in Biometrics.

## Functions in SurvGSD

 Name Description General.tau Information fractions under a generalized gamma survival distribution or a log-logistic survival distribution. Find.h To find parameter of a uniform dropout censoring distribution under a generalized gamma survival distribution or a log-logistic survival distribution. SSize.FixAlter Maximum sample size for a group sequential test under a generalized gamma survival distribution or a log-logistic survival distribution. No Results!