TCGAretriever (version 1.3)

get_ext_mutation: Retrieve Extended Information About DNA Mutations from TCGA

Description

Query TCGA for Data about DNA Sequence Variations (Mutations) identified by exome sequencing projects. The function will retrieve an extensive set of information for each mutation that was identified in the set of cases of interest. The function can only handle a limited number of query genes. For larger queries, use the fetch_all_tcgadata() function.

Usage

get_ext_mutation(case_id = NULL, gprofile_id = NULL, glist = NULL)

Arguments

case_id

String corresponding to the Identifier of the case_list of interest

gprofile_id

String corresponding to the Identifier of the Genetic Profile of Interest

glist

Character vector including Gene Identifiers (ENTREZID or OFFICIAL_SYMBOL)

Value

Data Frame inluding one row per mutation

References

http://www.biotechworld.it/bioinf/2016/07/11/tcga-data-via-tcgaretriever/

Examples

# NOT RUN {
tp53_mutats <- get_ext_mutation("blca_tcga_all", "blca_tcga_mutations", "TP53")
if(ncol(tp53_mutats) >= 6 & nrow(tp53_mutats) >= 10){
tp53_mutats[1:10,1:6]
}
# }