est.FDR.hat.l

min.x

max.x

c.prev

Vector of number of pooled observations in layer l bins

Vector of case counts in each bin at layer l

Nominal boundary level for binomial parameter at layer 1

theta0

Step-down multiple-testing procedure

An implementation of the TEAM algorithm to identify local differences
between two (e.g. case and control) independent, univariate distributions, as
described in J Pura, C Chan, and J Xie (2019) <arXiv:1906.07757>. The algorithm
is based on embedding a multiple-testing procedure on a hierarchical structure
to identify high-resolution differences between two distributions. The
hierarchical structure is designed to identify strong, short-range differences
at lower layers and weaker, but long-range differences at increasing layers.
TEAM yields consistent layer-specific and overall false discovery rate control.

est.FDR.hat.l: Calculate FDR

Description

Usage

Arguments