Characterization of functional genes in complex microbial
communities using tiling DNA microarrays
Description
This package is intended for processing the output from
functional gene tiling DNA microarray experiments. It produces
hybridization pattern plots for each gene on the array, and
statistics for each gene including mean probe intensity, median
probe intensity, bright probe fraction, bright segment length
dependent score, bright probe mean intensity, and bright probe
median intensity. Output is generated in order of bright
segment length dependent score in both a latex/eps format and
tab-delimited text file. The package works in two modes: single
array, and comparison of two arrays. Array comparison includes
array comparison statistics: median of logarithm of one array
probe divided by its counterpart on the other array, median
absolute deviation of that value, and the binomial test to see
whether the genes are equally abundant in both arrays.