ToxicoGx (version 0.1.1)

geneDrugPerturbation: Compute gene-drug associations

Description

Function computing gene-drug associations from perturbation data

Usage

geneDrugPerturbation(x, concentration, type, batch, duration, model = FALSE)

Arguments

x

[numeric] Vector of gene expression values

concentration

[numeric] Vector with drug concentrations/doses

type

[factor] Vector of factors specifying the cell lines or type types

batch

[factor] Vector of factors specifying the batch

duration

[character] Vector of measurement times (in hours)

model

[logical] Should the full linear model be returned? Default set to FALSE

Value

[numeric] Vector reporting the effect size (estimateof the coefficient of drug concentration), standard error (se), sample size (n), t statistic, and F statistics and its corresponding p-value