te_outcome_model-class

Implements target trial emulation methods to apply randomized
clinical trial design and analysis in an observational setting. Using
marginal structural models, it can estimate intention-to-treat and
per-protocol effects in emulated trials using electronic health
records. A description and application of the method can be found in
Danaei et al (2013) <doi:10.1177/0962280211403603>.

Isaac Gravestock

TrialEmulation

Causal Analysis of Observational Time-to-Event Data

Li Su

Roonak Rezvani

Julia Moesch

Medical Research Council (MRC) 

F. Hoffmann-La Roche AG 

te_outcome_model-class function

<dl>
<dt><code>formula</code></dt>
<dd><code>formula</code> object for the model fitting</dd></dl>
<dt><code>adjustment_vars</code></dt>
<dd>character. Adjustment variables</dd>
<dt><code>treatment_var</code></dt>
<dd>Variable used for treatment</dd>
<dt><code>stabilised_weights_terms</code></dt>
<dd>formula. Adjustment terms from numerator models of stabilised weights. These must be
included in the outcome model.</dd>
<dt><code>adjustment_terms</code></dt>
<dd>formula. User specified terms to include in the outcome model</dd>
<dt><code>treatment_terms</code></dt>
<dd>formula. Estimand defined treatment term</dd>
<dt><code>followup_time_terms</code></dt>
<dd>formula. Terms to model follow up time within an emulated trial</dd>
<dt><code>trial_period_terms</code></dt>
<dd>formula. Terms to model start time ("trial_period") of an emulated trial</dd>
<dt><code>model_fitter</code></dt>
<dd>Model fitter object</dd>
<dt><code>fitted</code></dt>
<dd>list. Saves the model objects</dd>

Slots

Fitted Outcome Model Object — te_outcome_model-class

<dl>
<dt><code>formula</code></dt>
<dd><code>formula</code> object for the model fitting</dd>


<dt><code>adjustment_vars</code></dt>
<dd>character. Adjustment variables</dd>


<dt><code>treatment_var</code></dt>
<dd>Variable used for treatment</dd>


<dt><code>stabilised_weights_terms</code></dt>
<dd>formula. Adjustment terms from numerator models of stabilised weights. These must be
included in the outcome model.</dd>


<dt><code>adjustment_terms</code></dt>
<dd>formula. User specified terms to include in the outcome model</dd>


<dt><code>treatment_terms</code></dt>
<dd>formula. Estimand defined treatment term</dd>


<dt><code>followup_time_terms</code></dt>
<dd>formula. Terms to model follow up time within an emulated trial</dd>


<dt><code>trial_period_terms</code></dt>
<dd>formula. Terms to model start time ("trial_period") of an emulated trial</dd>


<dt><code>model_fitter</code></dt>
<dd>Model fitter object</dd>


<dt><code>fitted</code></dt>
<dd>list. Saves the model objects</dd>


</dl>

Fitted Outcome Model Object

te_outcome_model-class: Fitted Outcome Model Object

Description

Arguments

Slots