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TrialSimulator (version 1.10.1)

add_arms: Adding One or More Arms to a Trial

Description

add one or more arms to a trial. This function can be used in two scenarios: (1) adding arms right after a trial is created (i.e., trial(...)). sample_ratio and arms added through ... must be of same length; (2) adding arms to an existing trial in action functions of milestones.

This is a user-friendly wrapper of the member function of trial, i.e., Trials$add_arms(), which is used in vignettes. Users who are not familiar with the concept of classes may consider using this wrapper directly.

Usage

add_arms(trial, sample_ratio, ...)

Arguments

trial

a trial object returned by trial().

sample_ratio

integer vector. Sample ratio for permuted block randomization. It will be appended to existing sample ratio in the trial.

...

one or more objects returned from arm(). Randomization is carried out with updated sample ratio of newly added arm. Note that we can run Trials$add_arm(sample_ratio1, arm1) followed by add_arms(trial, sample_ratio2, arm2). We would expected similar result with add_arms(trial, c(sample_ratio1, sample_ratio2), arm1, arm2). Note that these two methods won't return exactly the same trial because randomization queue are generated twice in the first approach but only once in the second approach. But statistically, they are equivalent and of the same distribution.