censordata

simdata

lambda

gamma

Patient dropout rate with range [0,1). If dropoutrate contains only one number. The program will control the dropout rate at population level(treatment + control). If dropoutrate contains two numbers (ie. c(0.2,0.1)), the program will control the dropout rate of control and treatment arm seperately, with the first dropout rate number for control and the second number for treatment. Default value is "0" (no dropout)

dropoutrate

exp(beta*x), if there's no covariates, ebx=1.

frequence of each level of ebx value

groupfreq

time intervals for piecewise baseline hazard function

timeinterval

gamma for censor hazard function. Default is 1 (exponential)

gammac

censor hazard distribution. Default is exponential

censordist

Indicator of piecewise hazard ratios. TURE for piecewise. FALSE for non piecewise

HRPW

Censor events given a fixed dropout rate

A system to simulate clinical trials with time to event endpoints. Event simulation is based on Cox models allowing for covariates in addition to the treatment or group factor. Specific drop-out rates (separate from administrative censoring) can be controlled in the simulation. Other features include stratified randomization, non-proportional hazards, different accrual patterns, and event projection (timing to reach the target event) based on interim data.

censordata: Censor Events Given a Fixed Dropout Rate

Description

Usage

Arguments