objfunction

Censor hazard function parameter. For exponential or weibull censor hazard, x is lambda, for uniform hazard, x is the maximum time of the censoring window.

lambda

gamma

gamma for censor hazard function. THis is required if the censoring hazard function is weibull

gammac

theta

exp(beta*x), if there's no covariates, ebx=1.

frequence of each level of ebx value

groupfreq

censor hazard function distribution

censordist

time intervals for piecewise baseline hazard function

timeinterval

objective function for the finding of censor hazard function parameter.

A system to simulate clinical trials with time to event endpoints. Event simulation is based on Cox models allowing for covariates in addition to the treatment or group factor. Specific drop-out rates (separate from administrative censoring) can be controlled in the simulation. Other features include stratified randomization, non-proportional hazards, different accrual patterns, and event projection (timing to reach the target event) based on interim data.

objfunction: Objective Function for the Finding of Censor Hazard Function Parameter for Proportional Hazard Model

Description

Usage

Arguments