weibullsim_pw

lambda for event hazard function. It will be a vector for piecewise hazard function.

lambda

gamma for event hazard function. It will be a vector for piecewise hazard function.

gamma

betas

time intervals for piecewise weibull parameters.

Simulate event time with weibull hazard function given the piecewise parameters.

A system to simulate clinical trials with time to event endpoints. Event simulation is based on Cox models allowing for covariates in addition to the treatment or group factor. Specific drop-out rates (separate from administrative censoring) can be controlled in the simulation. Other features include stratified randomization, non-proportional hazards, different accrual patterns, and event projection (timing to reach the target event) based on interim data.

weibullsim_pw: Simulate event time with weibull hazard function. The parameters can be piecewise.

Description

Usage

Arguments