Fit proportional hazards models with a weighted cumulative exposure, based on a weight function estimated from cubic regression b-splines. This implementation of WCE assumes that the dataset is in the interval format with one line per unit of time.
Authors: Marie-Pierre Sylvestre, Marie-Eve Beauchamp, Ryan Patrick Kyle, Michal Abrahamowicz
Maintainer: Marie-Pierre Sylvestre <marie-pierre.sylvestre@umontreal.ca>
| Package: | WCE |
| Type: | Package |
| Version: | 1.0.2 |
| Date: | 2018-08-08 |
| License: | GPL-2 |
Sylvestre MP, Abrahamowicz M. Flexible modeling of the cumulative effects of time-dependent exposures on the hazard. Stat Med. 2009;28(27):3437-53.
Abrahamowicz M, Beauchamp M-E, Sylvestre M-P. Comparison of alternative models for linking drug exposure with adverse effects. Stat Med. 2012;31(11-12):1014-1030.