WWGbook (version 1.0.2)

rat.brain: rat.brain data in Chapter 5

Description

The data used in this example were originally reported by Douglas, et al. (2004). The aim of their experiment was to examine nucleotide activation (guanine nucleotide bonding) in seven different brain nuclei (i.e., brain regions) among five adult male rats.

Usage

data(rat.brain)

Format

A data frame with 30 observations on the following 4 variables.

animal

: Unique identifier for each rat

treatment

: Level of drug treatment (1 = Basal, 2 = Carbachol)

region

: Brain nucleus (1 = BST, 2 = LS, 3 = VDB)

activate

: Nucleotide activation (the dependent variable)

References

Douglas, C.L., Demarco, G.J., Baghdoyan, H.A., and Lydic, R, Pontine and basal forebrain cholinergic interaction: implications for sleep and breathing, Respiratory Physiology and Neurobiology, 143, 251, 2004.

West, B., Welch, K. & Galecki, A, Linear Mixed Models: A Practical Guide Using Statistical Software, Chapman Hall / CRC Press, first edition, 2006.

Examples

# NOT RUN {
attach(rat.brain)

region.f <- region
region.f[region == 1] <- 1
region.f[region == 2] <- 2
region.f[region == 3] <- 0
region.f <- factor(region.f)
treat <- treatment
treat[treatment == 1] <- 0
treat[treatment == 2] <- 1
treat <- factor(treat)
detach(rat.brain)
rat.brain <- data.frame(rat.brain, region.f, treat)
str(rat.brain)
# }