convertdf2enr

Converts a data frame containing enrichment results into a clusterProfiler enrichResult object.
Assumes the data frame has columns: ID, geneID, pvalue, and optionally p.adjust.

Tools to analyze sex differences in omics data for complex diseases. It includes functions for differential expression analysis using the 'limma' method <doi:10.1093/nar/gkv007>, interaction testing between sex and disease, pathway enrichment with 'clusterProfiler' <doi:10.1089/omi.2011.0118>, and gene regulatory network (GRN) construction and analysis using 'igraph'. The package enables a reproducible workflow from raw data processing to biological interpretation.

Enrico Glaab

XYomics

Analysis of Sex Differences in Omics Data for Complex Diseases

Sophie Le Bars

Mohamed Soudy

Murodzhon Akhmedov

convertdf2enr function

<dl><dt>df</dt>
<dd>Data frame containing enrichment results.</dd>
<dt>pvalueCutoff</dt>
<dd>Numeric. P-value cutoff for the enrichment object (default: 0.1).</dd>
<dt>pAdjustMethod</dt>
<dd>Character string specifying the p-value adjustment method (default: "BH").</dd></dl>

Arguments

Convert Data Frame to enrichResult — convertdf2enr

<dl>

<dt>df</dt>
<dd>Data frame containing enrichment results.</dd>


<dt>pvalueCutoff</dt>
<dd>Numeric. P-value cutoff for the enrichment object (default: 0.1).</dd>


<dt>pAdjustMethod</dt>
<dd>Character string specifying the p-value adjustment method (default: "BH").</dd>

</dl>

convertdf2enr: Convert Data Frame to enrichResult

Description

Usage

Value

Arguments