YPmodelPhreg-package

This package fits a semiparametric short term and long term hazard ratio model for the group variable, adjusted for proportional covariate effects. The model was studied in Yang and Prentice (2015), and it extends the two sample results in Yang and Prentice (2005). The model accommodates various non-proportional hazards scenarios including those with crossing hazards or survival functions. The main function of the package is <code>ypreg</code>, which provides the estimates and confidence intervals of the model parameters, the average hazard ratio, and the hazard ratios at user-specified time points. Plots of point-wise and simultaneous confidence bands are also given.

 package

Provides covariate-adjusted comparison of two groups of right
censored data, where the binary group variable has separate short-term
and long-term effects on the hazard function, while effects of covariates
such as age, blood pressure, etc. are proportional on the hazard. The model
was studied in Yang and Prentice (2015) <doi:10.1002/sim.6453> and it extends
the two sample version of the short-term and long-term hazard ratio model
proposed in Yang and Prentice (2005) <doi:10.1093/biomet/92.1.1>. The model
extends the usual Cox proportional hazards model to allow more flexible
hazard ratio patterns, such as gradual onset of effect, diminishing effect,
and crossing hazard or survival functions. This package provides
the following: 1) point estimates and confidence intervals for model
parameters; 2) point estimate and confidence interval of the average hazard
ratio; and 3) plots of estimated hazard ratio function with point-wise and
simultaneous confidence bands.

Daewoo Pak

YPmodelPhreg

The Short-Term and Long-Term Hazard Ratio Model with
Proportional Adjustment

Song Yang

YPmodelPhreg-package function

Daewoo Pak and Song Yang
Maintainer: Daewoo Pak &lt;dpak@yonsei.ac.kr&gt;

Author

This package fits a semiparametric short term and long term hazard ratio model for the group variable, adjusted for proportional covariate effects. The model was studied in Yang and Prentice (2015), and it extends the two sample results in Yang and Prentice (2005). The model accommodates various non-proportional hazards scenarios including those with crossing hazards or survival functions. The main function of the package is <code>ypreg</code>, which provides the estimates and confidence intervals of the model parameters, the average hazard ratio, and the hazard ratios at user-specified time points. Plots of point-wise and simultaneous confidence bands are also given.

Package:	YPmodelPhreg
Type:	Package
Version:	1.0.0
Date:	2023-04-21
License:	GPL (>= 3)

YPmodelPhreg-package: The Short-Term and Long-Term Hazard Ratio Model with Proportional Adjustment

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