check_slope_rule_overlap

Takes in tables with existing and incoming selections and exclusions, finds any overlap and
differences, edits the ruleset table accordingly.

An interactive 'shiny' application for performing non-compartmental analysis (NCA) on
pre-clinical and clinical pharmacokinetic data. The package builds on 'PKNCA' for core estimators and provides interactive visualizations, CDISC
outputs ('ADNCA', 'PP', 'ADPP') and configurable TLGs (tables, listings, and graphs). Typical use cases include exploratory
analysis, validation, reporting or teaching/demonstration of NCA methods. Methods and core
estimators are described in Denney, Duvvuri, and Buckeridge (2015) "Simple, Automatic
Noncompartmental Analysis: The PKNCA R Package" <doi:10.1007/s10928-015-9432-2>.

Valentin Legras

aNCA

(Pre-)Clinical NCA in a Dynamic Shiny App

Ercan Suekuer

Gerardo Jose Rodriguez

Pascal Baertschi

Jana Spinner

Mateusz Kolomanski

Lucy Aspridis

F. Hoffmann-La Roche AG 

check_slope_rule_overlap function

<dl><dt>existing</dt>
<dd>Data frame with existing selections and exclusions.</dd>
<dt>new</dt>
<dd>Data frame with new rule to be added or removed.</dd>
<dt>slope_groups</dt>
<dd>List with column names that define the groups.</dd>
<dt>.keep</dt>
<dd>Whether to force keep fully overlapping rulesets. If FALSE, it will be assumed
that the user wants to remove rule if new range already exists in the dataset.
If TRUE, in that case full range will be kept.</dd></dl>

Arguments

Check overlap between existing and new slope rulesets — check_slope_rule_overlap

<dl>

<dt>existing</dt>
<dd>Data frame with existing selections and exclusions.</dd>


<dt>new</dt>
<dd>Data frame with new rule to be added or removed.</dd>


<dt>slope_groups</dt>
<dd>List with column names that define the groups.</dd>


<dt>.keep</dt>
<dd>Whether to force keep fully overlapping rulesets. If FALSE, it will be assumed
that the user wants to remove rule if new range already exists in the dataset.
If TRUE, in that case full range will be kept.</dd>

</dl>

check_slope_rule_overlap: Check overlap between existing and new slope rulesets

Description

Usage

Value

Arguments