Learn R Programming

⚠️There's a newer version (1.50) of this package.Take me there.

aSPU (version 1.38)

Adaptive Sum of Powered Score Test

Description

R codes for the (adaptive) Sum of Powered Score ('SPU' and 'aSPU') tests, inverse variance weighted Sum of Powered score ('SPUw' and 'aSPUw') tests and gene-based and some pathway based association tests (Pathway based Sum of Powered Score tests ('SPUpath') and adaptive 'SPUpath' ('aSPUpath') test, Gene-based Association Test that uses an extended Simes procedure ('GATES'), Hybrid Set-based Test ('HYST'), extended version of 'GATES' test for pathway-based association testing ('Gates-Simes'). ). The tests can be used with genetic and other data sets with covariates. The response variable is binary or quantitative.

Copy Link

Version

Install

install.packages('aSPU')

Monthly Downloads

398

Version

1.38

License

GPL-3

Issues

Pull Requests

Stars

Forks

Maintainer

IlYoup Kwak

Last Published

October 26th, 2015

Functions in aSPU (1.38)

aSPUs

Sum of Powered Score (SPUs) tests and adaptive SPU (aSPUs) test with GWAS summary statistics.
aSPUsPath

Pathway based Sum of Powered Score tests (SPUsPath) and adaptive SPUpath (aSPUsPath) test with GWAS summary statistics.
getlogitp

Get the p-values of the multiple SNPs based on the Wald test in a logistic regresion model.
simPathAR1Snp

Simulating a pathway with multiple SNPs.
GATES2

Gene-based Association Test that uses an extended Simes procedure (GATES)
aSPUw

Inverse variance weighted Sum of Powered Score tests (SPUw) and adaptive SPUw (aSPUw) test.
GEEaSPU

GEEaSPU test for association with multiple traits in generalized estimation equations.
aSPUpath

Pathway based Sum of Powered Score tests (SPUpath) and adaptive SPUpath (aSPUpath) test.
exdat

An example data set
Hyst

HYST (Hybrid Set-based Test)
aSPUpathSingle

Single-gene based version of the Sum of Powered Score tests (SPUpathSingle) and adaptive SPUpathSingle (aSPUpathSingle) test.
GatesSimes

GATES-Simes test for pathway-based association testing
aSPU

Sum of Powered Score (SPU) tests and adaptive SPU (aSPU) test.
kegg9

A subset of coronary artery disease (CAD) data