abd (version 0.1-21)

LiverPreparation: Liver Preparation

Description

The unbound fraction of taurocholate for each of five concentrations of administered taurocholate.

Usage

data(LiverPreparation)

source

Smallwood, R.H., D.J. Morgan, G.W. Mihaly, and R.A. Smallwood. 1998. Effect of a protein binding change on unbound and total plasma concentrations for drugs of intermediate hepatic extraction. Journal of Pharmacokinetics and Pharmacodynamics 16:397-411.

References

http://www.springerlink.com/content/p134310534nw8j72

Examples

data(LiverPreparation)
str(LiverPreparation)
xyplot(unbound.fraction ~ concentration, LiverPreparation)